BDBM31876 2,4-Bisanilinopyrimidine, 42

SMILES COc1ccc(NC(=O)c2ccc(Nc3nc(Nc4ccc(O)cc4)ncc3F)cc2)cc1

InChI Key InChIKey=VLEHOZCAQJNQPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31876   

TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM31876(2,4-Bisanilinopyrimidine, 42)
Affinity DataIC50:  14nMAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed