BDBM319101 N-[(cyclopropyl- carbamoyl) methyl]-2-{5- fluoro-6-[4-(1H- pyrazol-5-yl) phenyl]-1,3- benzothiazol- 2-yl}-2-(3,3,3- trifluoropropane- sulfonyl) acetamide::US10173991, Example 144

SMILES Fc1cc2nc(sc2cc1-c1ccc(cc1)-c1ccn[nH]1)C(C(=O)NCC(=O)NC1CC1)S(=O)(=O)CCC(F)(F)F

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319101   

TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM319101(N-[(cyclopropyl- carbamoyl) methyl]-2-{5- fluoro-6...)
Affinity DataIC50:  1nMAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent