BDBM31916 Tryptophanhydroxamate, 13

SMILES c1ccc2c(c1)c(c[nH]2)C[C@@H](C(=O)NO)N

InChI Key InChIKey=LBMAEBPZXXNKMZ-UHFFFAOYSA-N

Data  5 Kd

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31916   

Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM31916(Tryptophanhydroxamate, 13)
Affinity DataKd:  3.60E+4nMAssay Description:Binding affinity to Burkholderia pseudomallei IspF at pH 7.4 measured by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM31916(Tryptophanhydroxamate, 13)
Affinity DataKd:  8.48E+5nMAssay Description:Binding affinity to Burkholderia pseudomallei IspF at pH 6 measured by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Burkholderia pseudomallei (strain K96243))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM31916(Tryptophanhydroxamate, 13)
Affinity DataKd:  2.40E+4nMAssay Description:Binding affinity to Burkholderia pseudomallei IspF at pH 8 measured by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase(Escherichia coli (strain K12))
Northern Illinois University

Curated by ChEMBL
LigandPNGBDBM31916(Tryptophanhydroxamate, 13)
Affinity DataKd:  2.20E+4nMAssay Description:Binding affinity to Escherichia coli IspF at pH 7.4 measured by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed