BDBM320395 2-[hydroxy(oxan-4-yl)methyl]- 1H-pyrrolo[3,2-b]pyridine- 7-carboxylic acid::US10174026, Example 43::US9738637, Example 43

SMILES OC(C1CCOCC1)c1cc2nccc(C(O)=O)c2[nH]1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 320395   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quantical Research

US Patent
LigandPNGBDBM320395(2-[hydroxy(oxan-4-yl)methyl]- 1H-pyrrolo[3,2-b]pyr...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Celgene Quantical Research

US Patent
LigandPNGBDBM320395(2-[hydroxy(oxan-4-yl)methyl]- 1H-pyrrolo[3,2-b]pyr...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quantical Research

US Patent
LigandPNGBDBM320395(2-[hydroxy(oxan-4-yl)methyl]- 1H-pyrrolo[3,2-b]pyr...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quantical Research

US Patent
LigandPNGBDBM320395(2-[hydroxy(oxan-4-yl)methyl]- 1H-pyrrolo[3,2-b]pyr...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent