BDBM320941 (R)- or (S)-1-(1-(4- (Difluoromethyl)phenyl) propyl)-6-(dimethylamino)- 3-(fluoromethyl)-1H- pyrazolo[3,4- d]pyrimidin-4(5H)-one::US10174037, Example 346::US10174037, Example 347
SMILES CCC(c1ccc(cc1)C(F)F)n1nc(CF)c2c1nc([nH]c2=O)N(C)C
InChI Key
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 320941
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.0800nMAssay Description:Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 6.5nMAssay Description:Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor...More data for this Ligand-Target Pair