BDBM321034 4-Amino-7-[(1R,2S,3R,4R)-2,3-dihydroxy-4-[(sulfamoylamino)methyl]cyclopentyl]-5-[2-(2-ethylsulfonyl-6-fluoro-4-pyrrolidin-1-yl-phenyl)ethynyl]pyrrolo[2,3-d]pyrimidine::US10174040, Example 114

SMILES CCS(=O)(=O)c1cc(cc(F)c1C#Cc1cn([C@@H]2C[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12)N1CCCC1

InChI Key InChIKey=KKOUHJSEBBTPEJ-RWJCITIMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321034   

TargetNEDD8-conjugating enzyme UBE2F(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321034(4-Amino-7-[(1R,2S,3R,4R)-2,3-dihydroxy-4-[(sulfamo...)
Affinity DataIC50: <3nMAssay Description:A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent