BDBM321074 8-((2-amino-2,4-dimethylpentyl)oxy)benzo[c][1,7]naphthyridin-6(5H)-one::US10174044, Example 8

SMILES COc1ccc(Cn2c3cnccc3c3ccc(OCC(C)(CC(C)C)NC(=O)OC(C)(C)C)cc3c2=O)cc1

InChI Key InChIKey=ILKLUGNPAATPOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321074   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM321074(8-((2-amino-2,4-dimethylpentyl)oxy)benzo[c][1,7]na...)
Affinity DataIC50:  2.60nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent