BDBM321348 3-({[(1R)-6-methoxy-1,2,3,4- tetrahydronaphthalen-1-yl]-methyl} amino)pyridine-4-carboxylic acid::US10179769, Example 62::US10807956, Example 62::US11214542, Example 62::US11639333, Example 62
SMILES COc1ccc2[C@H](CNc3cnccc3C(O)=O)CCCc2c1
InChI Key InChIKey=NXQKMWGCRMQRSS-ZDUSSCGKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 321348
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Affinity DataEC50: 560nMAssay Description:Inhibition of full-length KDM4C (unknown origin) expressed in human KYSE-150 cells assessed as increase in H3K36me3 level after 24 hrs by Western blo...More data for this Ligand-Target Pair