BDBM322086 1-[5-(Benzyloxy)-1-(2-cyclopentylethyl)-1H-pyrazol-3-yl]-N-methylmethanamine::US10183913, Example 192::US11312688, Example 192

SMILES CNCc1cc(OCc2ccccc2)n(CCC2CCCC2)n1

InChI Key InChIKey=BZZQBKFMTJPRQX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 322086   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM322086(1-[5-(Benzyloxy)-1-(2-cyclopentylethyl)-1H-pyrazol...)
Affinity DataKi:  0.910nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM322086(1-[5-(Benzyloxy)-1-(2-cyclopentylethyl)-1H-pyrazol...)
Affinity DataKi:  0.910nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM322086(1-[5-(Benzyloxy)-1-(2-cyclopentylethyl)-1H-pyrazol...)
Affinity DataKi:  3.90nMAssay Description:A solution of 200 μL in total was prepared by mixing 50 μL of [3H] mesulergine (manufactured by GE Healthcare) diluted with 50 mmol/L Tris-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM322086(1-[5-(Benzyloxy)-1-(2-cyclopentylethyl)-1H-pyrazol...)
Affinity DataKi:  3.90nMAssay Description:A solution of 200 μL in total was prepared by mixing 50 μL of [3H] mesulergine (manufactured by GE Healthcare) diluted with 50 mmol/L Tris-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent