BDBM323081 4-((trans-4-(4-chlorophenyl)piperidin-3-yl(methoxy)-2,5-difluoro-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide::US9630929, Example 51

SMILES Fc1cc(c(F)cc1OC[C@@H]1CNCCC1c1ccc(Cl)cc1)S(=O)(=O)Nc1nncs1

InChI Key InChIKey=OGCZSSQTZGUXFG-CFMCSPIPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323081   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM323081(4-((trans-4-(4-chlorophenyl)piperidin-3-yl(methoxy...)
Affinity DataIC50:  84.4nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM323081(4-((trans-4-(4-chlorophenyl)piperidin-3-yl(methoxy...)
Affinity DataIC50: <100nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent