BDBM32327 4-amino-6,7-dimethoxy-3-(3-morpholin-4-ylpropyl)quinazoline-2-thione::4-amino-6,7-dimethoxy-3-(3-morpholinopropyl)quinazoline-2-thione::4-amino-6,7-dimethoxy-3-[3-(4-morpholinyl)propyl]-2-quinazolinethione::4-azanyl-6,7-dimethoxy-3-(3-morpholin-4-ylpropyl)quinazoline-2-thione::4-imino-6,7-dimethoxy-3-(3-morpholinopropyl)-3,4-dihydro-2(1H)-quinazolinethione::MLS000720534::SMR000336049::cid_1482788
SMILES COc1cc2nc(=S)n(CCCN3CCOCC3)c(N)c2cc1OC
InChI Key InChIKey=ARRCDBJNLBSMND-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 32327
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc
Curated by PubChem BioAssay
Nmmlsc
Curated by PubChem BioAssay
Affinity DataEC50: 1.09E+4nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Nmmlsc
Curated by PubChem BioAssay
Nmmlsc
Curated by PubChem BioAssay
Affinity DataEC50: 6.14E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
Affinity DataEC50: 9.25E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair