BDBM323447 3-Amino-1-(3-(Cycloheptylmethoxy)Phenyl)Propan-1-One::US10188615, Example 16::US10639286, Example 16

SMILES NCCC(=O)c1cccc(OCC2CCCCCC2)c1

InChI Key InChIKey=POHAQOMTRQSQBF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 323447   

TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323447(3-Amino-1-(3-(Cycloheptylmethoxy)Phenyl)Propan-1-O...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinaldehyde-binding protein 1(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323447(3-Amino-1-(3-(Cycloheptylmethoxy)Phenyl)Propan-1-O...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J Biol. Chem. 274:8577-85 (1999).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinaldehyde-binding protein 1(Bovine)
Acucela

US Patent
LigandPNGBDBM323447(3-Amino-1-(3-(Cycloheptylmethoxy)Phenyl)Propan-1-O...)
Affinity DataIC50: <100nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J Biol. Chem. 274:8577-85 (1999).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Acucela

US Patent
LigandPNGBDBM323447(3-Amino-1-(3-(Cycloheptylmethoxy)Phenyl)Propan-1-O...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent