BDBM323450 (S)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-1-Ol::US10188615, Example 29::US10639286, Example 29

SMILES NCC[C@H](O)c1cccc(OCC2CCCCC2)c1

InChI Key InChIKey=WJIGGYYSZBWCGC-INIZCTEOSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 323450   

TargetRetinoid isomerohydrolase(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323450((S)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
TargetRetinaldehyde-binding protein 1(Homo sapiens (Human))
Acucela

US Patent
LigandPNGBDBM323450((S)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-...)
Affinity DataIC50:  55nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J Biol. Chem. 274:8577-85 (1999).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRetinaldehyde-binding protein 1(Bovine)
Acucela

US Patent
LigandPNGBDBM323450((S)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-...)
Affinity DataIC50: <100nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J Biol. Chem. 274:8577-85 (1999).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Acucela

US Patent
LigandPNGBDBM323450((S)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair