BDBM323639 (R)-2-(3-(2-ethoxy- phenoxy)piperidin-1-yl)-N- (2-(methylsulfonyl)ethyl) pyrimidine-5-carboxamide::US10188653, Example 19.8

SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCCS(C)(=O)=O

InChI Key InChIKey=SRPYMEIUWBDIGX-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 323639   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM323639((R)-2-(3-(2-ethoxy- phenoxy)piperidin-1-yl)-N- (2-...)
Affinity DataIC50:  102nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent