BDBM323768 6-Bromo-N-(4-carbamoyl-2-fluorophenyl)-3-methyl-2-phenylquinoline-4-carboxamide::US10189788, Example 48

SMILES Cc1c(nc2ccc(Br)cc2c1C(=O)Nc1ccc(cc1F)C(N)=O)-c1ccccc1

InChI Key InChIKey=PADUSOFNXSUKNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323768   

TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM323768(6-Bromo-N-(4-carbamoyl-2-fluorophenyl)-3-methyl-2-...)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human FPR expressed in human Chem-1 cells assessed as inhibition of PGF2alpha-induced calcium flux preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM323768(6-Bromo-N-(4-carbamoyl-2-fluorophenyl)-3-methyl-2-...)
Affinity DataIC50:  102nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent