BDBM323772 4-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}-3-[(methoxymethyl)sulfanyl]benzoic acid::US10189788, Example 52

SMILES COCSc1cc(ccc1NC(=O)c1c(C)c(nc2ccc(Br)cc12)-c1ccccc1)C(O)=O

InChI Key InChIKey=QADJPQCTRBIXAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323772   

TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM323772(4-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbon...)
Affinity DataIC50:  6nMAssay Description:For the characterization of test substances in respect of FP antagonism, the PGF2α-induced calcium flux in recombinant FP-expressing CHO cells w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM323772(4-{[(6-Bromo-3-methyl-2-phenylquinolin-4-yl)carbon...)
Affinity DataIC50:  17nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent