BDBM32530 arylsulfonylpiperazine, 2
SMILES FC(F)(F)c1cccnc1N1CCN(CC1)S(=O)(=O)c1ccccc1
InChI Key InChIKey=RNOYTDIICXQMFU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 32530
Affinity DataIC50: 45nM EC50: 724nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
Affinity DataIC50: 122nMAssay Description:Enzyme assays were performed using purified recombinant mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine en...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 122nMAssay Description:Inhibition of mouse liver microsome 11betaHSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human 11betaHSD1More data for this Ligand-Target Pair