BDBM327445 1-(4-amino-5-bromo-2-methoxyphenyl)-3-[1-butyl-4-piperidyl]propan-1-one::US9663465, 2

SMILES CCCCN1CCC(CCC(=O)c2cc(Br)ccc2OC)CC1

InChI Key InChIKey=UOOCXIPKYHHRRD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327445   

Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Universite De Caen

US Patent
LigandPNGBDBM327445(1-(4-amino-5-bromo-2-methoxyphenyl)-3-[1-butyl-4-p...)
Affinity DataKi:  8.90nMAssay Description:Prior to these competition studies, a series of saturation curves were performed in order to check whether the pharmacological parameters Kd, Bmax an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
Universite De Caen

US Patent
LigandPNGBDBM327445(1-(4-amino-5-bromo-2-methoxyphenyl)-3-[1-butyl-4-p...)
Affinity DataIC50:  445nMAssay Description:Acetylcholinesterase extracted from human erythrocytes (buffered aqueous solution, ≧500 units/mg, Sigma Aldrich) is diluted in a 20 mM HEPES bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent