BDBM327448 1-(4-amino-5-fluoro-2-methoxyphenyl)-3-[1-(cyclohexylmethyl)-4-piperidyl]propan-1-one::US9663465, 5

SMILES COc1cc(N)c(F)cc1C(=O)CCC1CCN(CC2CCCCC2)CC1

InChI Key InChIKey=PXUUPGSNIMQISW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327448   

Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Universite De Caen

US Patent
LigandPNGBDBM327448(1-(4-amino-5-fluoro-2-methoxyphenyl)-3-[1-(cyclohe...)
Affinity DataKi:  3.80nMAssay Description:Prior to these competition studies, a series of saturation curves were performed in order to check whether the pharmacological parameters Kd, Bmax an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
Universite De Caen

US Patent
LigandPNGBDBM327448(1-(4-amino-5-fluoro-2-methoxyphenyl)-3-[1-(cyclohe...)
Affinity DataIC50:  24nMAssay Description:Acetylcholinesterase extracted from human erythrocytes (buffered aqueous solution, ≧500 units/mg, Sigma Aldrich) is diluted in a 20 mM HEPES bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent