BDBM327916 5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)-N-(4-(3- methoxyphenoxy) phenyl)picolinamide::US10377742, Compound 57::US9663496, Compound 57

SMILES COc1cccc(Oc2ccc(NC(=O)c3ccc(cn3)C(=O)N3CCN(Cc4ccc(F)cc4)CC3)cc2)c1

InChI Key InChIKey=WDGGQCRMJXHVAD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327916   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327916(5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)-N-(4...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327916(5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)-N-(4...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent