BDBM328997 1137478-45-5::US11787792, Compound Y-152::US9663503, Compound Y-152
SMILES Cn1cc(cn1)-c1cnc(Nc2cnc(cn2)C#N)cc1NC[C@@H]1CNCCO1
InChI Key InChIKey=HGYKCQUYMKJVQI-HNNXBMFYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 328997
Affinity DataIC50: 2nMAssay Description:CHK1 kinase activity was measured in a microfluidic assay that monitors the separation of a phosphorylated product from its substrate. The assay was ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of CHK1 (unknown origin) using 5-FAM-KKKVSRSGLYRSPSMPENLNRPR-COOH peptide as substrate incubated for 1 hr in presence of ATP by caliper mi...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:CHK1 kinase activity was measured in a microfluidic assay that monitors the separation of a phosphorylated product from its substrate. The assay was ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sareum
Curated by ChEMBL
Sareum
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of [3H]astemizole from human ERG expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of CHK1 in human HT-29 cells assessed as abrogation of etoposide-induced G2 checkpoint arrest by ELISAMore data for this Ligand-Target Pair