BDBM329515 2-((1S,2S)-2-((2-methyl-5- (4-methylpyridin-2- yl)pyrimidin-4- yloxy)methyl)cyclopropyl) quinoline::US9663513, 128
SMILES Cc1ccnc(c1)-c1cnc(C)nc1OC[C@H]1CC1c1ccc2ccccc2n1
InChI Key InChIKey=ODSJTHTXEOYGDM-MRTLOADZSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 329515
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.120nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair