BDBM329528 1-(5-(2-methyl-4- (((1S,2S)-2-(5- methylpyridin-2- yl)cyclopropyl)methoxy) pyrimidin-5-yl)pyridin-2- yl)ethanol::US9663513, 141::US9663513, 148::US9663513, 149

SMILES CC(O)c1ccc(cn1)-c1cnc(C)nc1OC[C@H]1C[C@@H]1c1ccc(C)cn1

InChI Key InChIKey=OIDDHCKMNIDRIN-QIWLAUOQSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 329528   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329528(1-(5-(2-methyl-4- (((1S,2S)-2-(5- methylpyridin-2-...)
Affinity DataKi:  0.140nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329528(1-(5-(2-methyl-4- (((1S,2S)-2-(5- methylpyridin-2-...)
Affinity DataKi:  0.240nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329528(1-(5-(2-methyl-4- (((1S,2S)-2-(5- methylpyridin-2-...)
Affinity DataKi:  0.980nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent