BDBM329549 1-(4-(4-(((1S,2S)-2-(5- ethylpyridin-2- yl)cyclopropyl)methoxy)- 2-methylpyrimidin-5-yl)- 1-methyl-1H-pyrazol-3- yl)ethanol::US9663513, 162::US9663513, 163

SMILES CCc1ccc(nc1)[C@H]1C[C@@H]1COc1nc(C)ncc1-c1cn(C)nc1C(C)O

InChI Key InChIKey=BIABLZQEFRAOMM-IIZJFRANSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329549   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329549(1-(4-(4-(((1S,2S)-2-(5- ethylpyridin-2- yl)cyclopr...)
Affinity DataKi:  0.130nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329549(1-(4-(4-(((1S,2S)-2-(5- ethylpyridin-2- yl)cyclopr...)
Affinity DataKi:  0.240nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent