BDBM329567 2-(5-(4-(((1S,2S)-2-(5- ethylpyridin-2- yl)cyclopropyl)methoxy)- 2-methylpyrimidin-5- yl)pyridin-2-yl)propan- 2-ol (enantiomer A)::US9663513, 180::US9663513, 181

SMILES CCc1ccc(nc1)[C@H]1C[C@@H]1COc1nc(C)ncc1-c1ccc(nc1)C(C)(C)O

InChI Key InChIKey=DBZCBAVXZUHVOJ-MOPGFXCFSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329567   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329567(2-(5-(4-(((1S,2S)-2-(5- ethylpyridin-2- yl)cyclopr...)
Affinity DataKi:  0.0500nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329567(2-(5-(4-(((1S,2S)-2-(5- ethylpyridin-2- yl)cyclopr...)
Affinity DataKi:  5.95nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent