BDBM329577 2-((1S,2S)-2-((2- methyl-5-(1,4- dioxaspiro[4.5]decan-8- yl)pyrimidin-4- yloxy)methyl) cyclopropyl)quinoline::US9663513, 190

SMILES Cc1ncc(C2CCC3(CC2)OCCO3)c(OC[C@H]2C[C@@H]2c2ccc3ccccc3n2)n1

InChI Key InChIKey=CRMUWPFYEWWQJQ-RTWAWAEBSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329577   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329577(2-((1S,2S)-2-((2- methyl-5-(1,4- dioxaspiro[4.5]de...)
Affinity DataKi:  0.0600nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent