BDBM329743 Preparation of ethyl [6-(3-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1]benzazepin-4-yl]acetate::US9663523, Example 7

SMILES CCOC(=O)CC1C=C(c2cccc(Cl)c2)c2ccccc2-n2c(C)nnc12

InChI Key InChIKey=BHPLVDJPOVUPKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329743   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329743(Preparation of ethyl [6-(3-chlorophenyl)-1-methyl-...)
Affinity DataIC50:  230nMAssay Description:For this purpose, a time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used, which measures the binding between N-terminally Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent