BDBM331402 11-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]-8-[(S)-(2-fluorophenyl)(oxan-4-yl)methyl]-5-[4-(2H3)methyl-1-methyl-1H-1,2,3-triazol-5-yl]-3,8,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2::US9725449, Example 237

SMILES C[C@H]1CN(C[C@@H](C)O1)c1ccc2c(n1)n([C@@H](C1CCOCC1)c1ccccc1F)c1cc(cnc21)-c1c(C)nnn1C

InChI Key InChIKey=IOOLJDYHAXYOSK-SQDCYFTFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 331402   

TargetBromodomain-containing protein 4 [1-477]/[333-460]/[44-168]/[44-460](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM331402(11-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]-8-[(S)-(2-...)
Affinity DataIC50: <1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent