BDBM331422 N-[2-(Dimethylamino)ethyl]-N-ethyl-8-[(S)-(2-fluorophenyl)(oxan-4-yl)methyl]-5-(4-methoxy-1-methyl-1H-1,2,3-triazol-5-yl)-3,8,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2::US9725449, Example 257

SMILES CCN(CCN(C)C)c1ccc2c(n1)n([C@@H](C1CCOCC1)c1ccccc1F)c1cc(cnc21)-c1c(OC)nnn1C

InChI Key InChIKey=HIOKVUGRWCOCLE-LJAQVGFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 331422   

TargetBromodomain-containing protein 4 [1-477]/[333-460]/[44-168]/[44-460](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM331422(N-[2-(Dimethylamino)ethyl]-N-ethyl-8-[(S)-(2-fluor...)
Affinity DataIC50: <1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent