BDBM331501 8-[(S)-(3-Fluoropyridin-2-yl)(oxan-4-yl)methyl]-10-methanesulfonyl-5-[4-(2H3)methyl-1-methyl-1H-1,2,3-triazol-5-yl]-N-(2,2,2-trifluoroethyl)-3,8,12-triazatricyclo[7.4.0.02,7]trideca-1(13),2::US9725449, Example 341
SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ncccc1F)c1c(cnc(NCC(F)(F)F)c21)S(C)(=O)=O
InChI Key InChIKey=MZSNRYYNHAHFDP-VWLOTQADSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 331501
TargetBromodomain-containing protein 4 [1-477]/[333-460]/[44-168]/[44-460](Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: <1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair