BDBM332014 (R)- or (S)-6''- (1-(4-(1,1- difluoro- ethyl)phenyl) ethyl)-2- methyl-[4,4''- bipyrimidin]- 6(1H)-one::US10195201, Example 36::US10195201, Example 37

SMILES CC(c1ccc(cc1)C(C)(F)F)c1cc(ncn1)-c1cc(=O)[nH]c(C)n1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 332014   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM332014((R)- or (S)-6''- (1-(4-(1,1- difluoro- ethyl)pheny...)
Affinity DataKi:  20nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM332014((R)- or (S)-6''- (1-(4-(1,1- difluoro- ethyl)pheny...)
Affinity DataKi:  65nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent