BDBM33251 phthalazine-based compound, 2
SMILES C1CN=C(N1)c1ccc(Nc2nnc(Nc3ccc(cc3)-c3ccccc3)c3ccccc23)cc1
InChI Key InChIKey=BTZWYGLEDWVKKG-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 33251
TargetGenome polyprotein [1393-1439,E1407V]/[1476-1660,R1508K,A1566M](Dengue virus 1(Hawaii))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 2.30E+3nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1394-1440]/[1476-1660](Dengue virus 4 (H241))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1394-1440]/[1476-1660,T1585M](Dengue virus 3 (strain S221/03))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 3.60E+3nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair