BDBM337664 US10227295, Compound JB6-22::US9751832, Compound JB6-22
SMILES CCCCN(Cc1ccc(cc1)C(=O)NO)C(=O)Nc1ncccn1
InChI Key InChIKey=NGUQTALSXMYZCZ-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 337664
TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute
US Patent
H. Lee Moffitt Cancer Center and Research Institute
US Patent
Affinity DataIC50: 2.74E+3nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute
US Patent
H. Lee Moffitt Cancer Center and Research Institute
US Patent
Affinity DataIC50: 9.76nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute
US Patent
H. Lee Moffitt Cancer Center and Research Institute
US Patent
Affinity DataIC50: 2.74E+3nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute
US Patent
H. Lee Moffitt Cancer Center and Research Institute
US Patent
Affinity DataIC50: 9.76nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute
US Patent
H. Lee Moffitt Cancer Center and Research Institute
US Patent
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human full length HDAC6 expressed in baculovirus infected Sf9 insect cells using p53 (379 to 382 residues) derived RHKKAc a...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute
US Patent
H. Lee Moffitt Cancer Center and Research Institute
US Patent
Affinity DataIC50: 2.74E+3nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair