BDBM337747 Ethyl 3-[2-chloro-3-(trifluoromethyl)benzyl]-1-[3,5-dichloro-4-(2-oxoimidazolidin-1-yl)phenyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate::US9751843, 127

SMILES CCOC(=O)c1cn(-c2cc(Cl)c(N3CCNC3=O)c(Cl)c2)c(=O)n(Cc2cccc(c2Cl)C(F)(F)F)c1=O

InChI Key InChIKey=BEACBSDQTZFXSK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337747   

TargetChymase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337747(Ethyl 3-[2-chloro-3-(trifluoromethyl)benzyl]-1-[3,...)
Affinity DataIC50:  49nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent