BDBM337764 1-[2-Fluoro-4-(2-oxo-1,3-oxazolidin-3-yl)phenyl]-3-[2-methyl-3-(trifluoromethyl)benzyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid::US9751843, 157

SMILES Cc1c(Cn2c(=O)c(cn(-c3ccc(cc3F)N3CCOC3=O)c2=O)C(O)=O)cccc1C(F)(F)F

InChI Key InChIKey=SRONGWDIIKNKST-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337764   

TargetChymase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337764(1-[2-Fluoro-4-(2-oxo-1,3-oxazolidin-3-yl)phenyl]-3...)
Affinity DataIC50:  31nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent