BDBM337790 3-(4-Chloro-2,3-dihydro-1H-inden-1-yl)-1-(3,4-dimethoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid (racemate)::US9751843, 184

SMILES COc1ccc(cc1OC)-n1cc(C(O)=O)c(=O)n(C2CCc3c2cccc3Cl)c1=O

InChI Key InChIKey=HPFVKJNKBOBEII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337790   

TargetChymase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337790(3-(4-Chloro-2,3-dihydro-1H-inden-1-yl)-1-(3,4-dime...)
Affinity DataIC50:  64nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent