BDBM337794 1-[3-Chloro-4-(2-oxo-1,3-oxazolidin-3-yl)phenyl]-2,4-dioxo-3-[(1R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid::US9751843, 188

SMILES OC(=O)c1cn(-c2ccc(N3CCOC3=O)c(Cl)c2)c(=O)n(C2CCc3c2cccc3C(F)(F)F)c1=O

InChI Key InChIKey=QLZBIOGOWVDBTO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337794   

TargetChymase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337794(1-[3-Chloro-4-(2-oxo-1,3-oxazolidin-3-yl)phenyl]-2...)
Affinity DataIC50:  66nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent