BDBM340035 1-(4-cyano-3-fluorophenyl)-3-(3-fluoro-4- (7-(5-methyl-1H-imidazol-2-yl)-1- oxoisoindolin-4-yl)phenyl)urea::US10604508, Compound 15::US11230539, Compound 15::US9758508, Compound 15

SMILES Cc1cnc([nH]1)-c1ccc(c2CNC(=O)c12)-c1ccc(NC(=O)Nc2ccc(C#N)c(F)c2)cc1F

InChI Key InChIKey=RTEPCLQSSPPCPB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 340035   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340035(1-(4-cyano-3-fluorophenyl)-3-(3-fluoro-4- (7-(5-me...)
Affinity DataIC50:  5nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340035(1-(4-cyano-3-fluorophenyl)-3-(3-fluoro-4- (7-(5-me...)
Affinity DataIC50:  5nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340035(1-(4-cyano-3-fluorophenyl)-3-(3-fluoro-4- (7-(5-me...)
Affinity DataIC50:  5nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent