BDBM340643 N-(4′-(2-tert-Butylphenoxy)-4-methoxy-3′-(3-p-tolylureido)biphenyl-3-yl)-1,1,1-trifluoromethanesulfonamide::US9765018, Example 7

SMILES COc1ccc(cc1NS(=O)(=O)C(F)(F)F)-c1ccc(Oc2ccccc2C(C)(C)C)c(NC(=O)Nc2ccc(C)cc2)c1

InChI Key InChIKey=KOEYZOXREHBNRU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340643   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM340643(N-(4′-(2-tert-Butylphenoxy)-4-methoxy-3̸...)
Affinity DataIC50:  750nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent