BDBM340786 (E)-1-(4-Prop oxy-2′-(1H-tetrazol-5-yl)-5-(4,4,4-trifluorobut-2-en-1-yl)-[1,1′-biphenyl]-3-yl)-3-(p-tolyl)urea::US9765018, Example 32

SMILES CCCOc1c(C\C=C/C(F)(F)F)cc(cc1NC(=O)Nc1ccc(C)cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=VGNLKBNLCFWJDG-NSIKDUERSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340786   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM340786((E)-1-(4-Prop oxy-2′-(1H-tetrazol-5-yl)-5-(4...)
Affinity DataIC50:  10nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent