BDBM340794 4'-(2-(tert-butyl) phenoxy)-3'-(3-(2- fluorophenyl)ureido)-4- methoxy-[1,1'-biphenyl]- 3-carboxylic acid::US9765018, Example 79

SMILES COc1ccc(cc1C(O)=O)-c1ccc(Oc2ccccc2C(C)(C)C)c(NC(=O)Nc2ccccc2F)c1

InChI Key InChIKey=XAJOXNWLUKPUDW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 340794   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM340794(4'-(2-(tert-butyl) phenoxy)-3'-(3-(2- fluorophenyl...)
Affinity DataIC50:  420nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM340794(4'-(2-(tert-butyl) phenoxy)-3'-(3-(2- fluorophenyl...)
Affinity DataIC50:  130nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCytochrome P450 2C8(Homo sapiens (Human))TBA
LigandPNGBDBM340794(4'-(2-(tert-butyl) phenoxy)-3'-(3-(2- fluorophenyl...)
Affinity DataIC50:  5.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))TBA
LigandPNGBDBM340794(4'-(2-(tert-butyl) phenoxy)-3'-(3-(2- fluorophenyl...)
Affinity DataEC50:  5.60E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM340794(4'-(2-(tert-butyl) phenoxy)-3'-(3-(2- fluorophenyl...)
Affinity DataIC50: >7.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails