BDBM34143 CHEMBL175835::E-6837

SMILES CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3ccc4c(Cl)cccc4c3)cc12

InChI Key InChIKey=OOIQBABUMXSCPC-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 34143   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM34143(CHEMBL175835 | E-6837)
Affinity DataKi:  0.200nMAssay Description:Inhibition of [3H]-LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM34143(CHEMBL175835 | E-6837)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM34143(CHEMBL175835 | E-6837)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM34143(CHEMBL175835 | E-6837)
Affinity DataKi:  0.700nM ΔG°:  -13.0kcal/mole EC50:  0.290nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed