BDBM345255 US10202350, Example 1::US11724989, Example 1

SMILES CC(C)(OCc1cc(-c2ccccc2)n(Cc2cccc(Cl)c2)n1)C(O)=O

InChI Key InChIKey=WRHIJCMSABCMKG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 345255   

TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM345255(US10202350, Example 1 | US11724989, Example 1)
Affinity DataIC50:  340nMAssay Description:MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM345255(US10202350, Example 1 | US11724989, Example 1)
Affinity DataIC50:  140nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM345255(US10202350, Example 1 | US11724989, Example 1)
Affinity DataIC50:  5.00E+4nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM345255(US10202350, Example 1 | US11724989, Example 1)
Affinity DataIC50:  340nMAssay Description:MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 4(Homo sapiens (Human))
Vettore

US Patent
LigandPNGBDBM345255(US10202350, Example 1 | US11724989, Example 1)
Affinity DataIC50:  140nMAssay Description:NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMalignant T-cell-amplified sequence 1(Homo sapiens (human))
Vettore

US Patent
LigandPNGBDBM345255(US10202350, Example 1 | US11724989, Example 1)
Affinity DataIC50:  5.00E+4nMAssay Description:MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent