BDBM345353 1-cyclobutyl-4-[1-[4-(4-pyridyl)phenyl]sulfonyl-4,5-dihydroimidazol-2-yl]piperazine::US10202354, Example 18

SMILES O=S(=O)(N1CCN=C1N1CCN(CC1)C1CCC1)c1ccc(cc1)-c1ccncc1

InChI Key InChIKey=LJUFLTZJYBIVAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345353   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345353(1-cyclobutyl-4-[1-[4-(4-pyridyl)phenyl]sulfonyl-4,...)
Affinity DataIC50:  0.0950nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent