BDBM345367 1-cyclobutyl-4-(1-tetralin-6-ylsulfonyl-4,5-dihydroimidazol-2-yl)piperazine::US10202354, Example 32

SMILES O=S(=O)(N1CCN=C1N1CCN(CC1)C1CCC1)c1ccc2CCCCc2c1

InChI Key InChIKey=JPPPBGVARYKPJW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345367   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345367(1-cyclobutyl-4-(1-tetralin-6-ylsulfonyl-4,5-dihydr...)
Affinity DataIC50:  0.0160nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In DepthDetails US Patent