BDBM345416 N-[2-chloro-4-[[2-(4-cyclobutylpiperazin-1-yl)-4,5-dihydroimidazol-1-yl]sulfonyl]phenyl]acetamide::US10202354, Example 81

SMILES CC(=O)Nc1ccc(cc1Cl)S(=O)(=O)N1CCN=C1N1CCN(CC1)C1CCC1

InChI Key InChIKey=RWJVIFMHWXPOFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345416   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345416(N-[2-chloro-4-[[2-(4-cyclobutylpiperazin-1-yl)-4,5...)
Affinity DataIC50:  0.127nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent