BDBM34545 MLS000104342::N-(2-pyridinyl)-2-pyridinecarbothioamide::N-(2-pyridyl)thiopicolinamide::N-pyridin-2-ylpyridine-2-carbothioamide::SMR000054277::cid_750538

SMILES S=C(Nc1ccccn1)c1ccccn1

InChI Key InChIKey=UGWOJXZJIZUKDP-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 34545   

TargetTranscription factor p65(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM34545(MLS000104342 | N-(2-pyridinyl)-2-pyridinecarbothio...)
Affinity DataEC50:  2.03E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCysteine protease ATG4B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM34545(MLS000104342 | N-(2-pyridinyl)-2-pyridinecarbothio...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of Atg4B (unknown origin) using LC3B-GST as substrate preincubated for 24 hrs followed by substrate addition measured for 3 mins by SDS-PA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM34545(MLS000104342 | N-(2-pyridinyl)-2-pyridinecarbothio...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of ATG4B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM34545(MLS000104342 | N-(2-pyridinyl)-2-pyridinecarbothio...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using GST-labelled LC3B as substrate after 24 hrs followed by substrate addition and measured after 3 mins by co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM34545(MLS000104342 | N-(2-pyridinyl)-2-pyridinecarbothio...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of ATG4B in human SAOS-2 cells using GFP-LC3B as substrate incubated for 6 hrs by by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM34545(MLS000104342 | N-(2-pyridinyl)-2-pyridinecarbothio...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of ATG4B (unknown origin) using LC3B-GST as substrate preincubated for 24 hrs followed by substrate addition measured after 3 mins by SDS-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed