BDBM346502 US10202378, Example 106::[3-(hydroxymethyl)phenyl]methyl4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-2,6-dimethyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-3-carboxylate

SMILES Cc1[nH]c2c(c1C(=O)OCc1cccc(CO)c1)c(cn(C)c2=O)C#CC(C)(O)C1CC1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346502   

TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
Genentech

US Patent
LigandPNGBDBM346502(US10202378, Example 106 | [3-(hydroxymethyl)phenyl...)
Affinity DataIC50:  166nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM346502(US10202378, Example 106 | [3-(hydroxymethyl)phenyl...)
Affinity DataIC50:  37.2nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent