BDBM347379 US10869871, ID # SW211668-(33291-R::US20230285402, ID # SW211668-(33291-R-isomer)::US9789116, SW211668

SMILES CCCC[S@@+]([O-])c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1

InChI Key InChIKey=LCYAYKSMOVLVRL-HHHXNRCGSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347379   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM347379(US10869871, ID # SW211668-(33291-R | US20230285402...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant human C-terminal 6xHis-tagged 15-PGDH expressed in Escherichia coli using PGE2 as substrate after 15 mins in presence of NA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM347379(US10869871, ID # SW211668-(33291-R | US20230285402...)
Affinity DataIC50:  1.34nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent