BDBM347426 US10869871, ID # SW209331::US20230285402, ID # SW209331::US9789116, SW209331

SMILES Nc1c(sc2nc(cc(-c3ccccc3)c12)-c1cccs1)[S+]([O-])CCCF

InChI Key InChIKey=CXQJAEMPTJFPNP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347426   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM347426(US10869871, ID # SW209331 | US20230285402, ID # SW...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of recombinant human C-terminal 6xHis-tagged 15-PGDH expressed in Escherichia coli using PGE2 as substrate after 15 mins in presence of NA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM347426(US10869871, ID # SW209331 | US20230285402, ID # SW...)
Affinity DataIC50:  6.14nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent